Gregory McManus Profile

Ph.D. in Chemistry, University of South Florida
B.S. in Chemistry, University of Prince Edward Island

Research Interests: Metal-Organic Frameworks, Porous Materials, Crystal Engineering, Climate Change, Crystallography
Teaching Interests: General Chemistry, Organic Chemistry, Inorganic Chemistry, Materials Chemistry

CHM 1045/L General Chemistry I lecture/lab
CHM 1046/L General Chemistry II lecture/lab
CHM 2210/L Organic Chemistry I lecture/lab
CHM 2211/L Organic Chemistry II lecture/lab
CHM 3610/L Inorganic Chemistry lecture/lab
CHM 4714C Materials Chemistry

• Burton, R.; Siegel, D.J.; Muller, J.E.; Regner, M.; Sheng, Y.; McManus, G.J.; MacDonald, J.H.; Mirjafari, M. "From gene delivery agents to ionic liquids: The impacts of cation structure and anion identity on liquefaction", J. Mol. Liq., 2019, 296, 111758.
• Hmissa, T.; Zhang, X.; Dhumal, N.R.; McManus, G.J.; Zhou, X.; Nulwala, H.B.; Mirjafari, A. "Autocatalytic Synthesis of Bifluoride Ionic Liquids by SuFEx Click Chemistry", Angew. Chem., 2018, 57, 16005-16009.
• Nestor, S.T.; Hawkins, A.N.; Xhani, X.; Sykora, R.E.; Mao, J.X.; Kwangho, N.; McManus, G.J.; Mirjafari, A. "Studies on Solubility and S-alkylation of 2-Thiouracil in Ionic Liquids", J. Mol. Liq., 2018, 265, 463-467.
• Nestor, S.T.; Heinrich, B.; Sykora, R.E.; Zhang, X.; McManus, G.J.; Douce, L.: Mirjafari, A. "Methimazolium-based ionic crystals: Emergence of mesomorphic properties via a sulfur motif", Tetrahedron, 2017, 36, 5456-5460.
• Zaworotko, M.J.; Hammud, H.H.; Kabbani, A.; McManus, G.J.; Ghannoum, A.M.; Masoud, M.S. "Synthesis and Characterization of Some Transition Metal Complexes with Mixed Adenine and Acetylacetonate Ligands: Crystal Structures of Solvated Complex {[Cu(acac)2(adenine)]•EtOH} and {[Cu(acac)2(adenine)]•DMF•H2O}", J. Chem. Cryst., 2009, 39, 853-863.
• Lawrence, H.R.; Li, Z; Richard Yip, M.L.; Sung, S.S.; Lawrence, N.J.; McLaughlin, M.L.; McManus, G.J.; Zaworotko, M.J.; Sebti, S.M.; Chen, J.; Guida, W.C. "Identification of a Disruptor of the MDM2-p53 Protein-Protein Interaction Facilitated by High-throughput in Silico Docking", Bioorg. Med. Chem. Lett., 2009, 19(14), 3756-3759.
• Naik, P.U.; McManus, G.J.; Zaworotko, M.J.; Singer, R.D. "Salicylaldoxime and salen containing imidazolium ionic liquids for biphasic catalysis and metal extractions", Dalton Trans., 2008, 4834-4836.
• McManus, G.J.; Wang, Z.; Beauchamp, D.A.; Zaworotko, M.J. "A novel metal-organic ternary topology constructed from triangular, square and tetrahedral molecular building blocks", Chem. Commun., 2007, 5212-5213.
• Perry, J.J.; Kravstov, V.Ch.; McManus, G.J.; Zaworotko, M.J. "Bottom up synthesis that does not start at the bottom: quadruple covalent cross-linking of nanoscale faceted polyhedra", J. Am. Chem. Soc., 2007, 129(33), 10076-10077.
• McManus, G.J.; Perry, J.J.; Perry, M.; Wagner, B.D.; Zaworotko, M.J. "Exciplex Fluorescence as a Diagnostic Probe of Structure in Coordination Polymers of Zn2+ and 4,4'-Bipyridine Containing Intercalated Pyrene and Enclathrated Aromatic Solvent Guests", J. Am. Chem. Soc., 2007, 129(29), 9094-9101.
• Larsen, R.W.; McManus, G.J.; Perry, J.J.; Rivera-Otero, E.; Zaworotko, M.J. "Spectroscopic Characterization of Hydroxylated Nanoballs in Methanol", Inorg. Chem., 2007, 46(15), 5904-5910.
• Cheney, M.L.; McManus, G.J.; Perman, J.A.; Wang, Z.; Zaworotko, M.J. "The role of co-crystals in solid-state synthesis: co-crystal controlled solid-state synthesis of imides", Cryst. Growth Des., 2007, 7(4), 616-617.
• Perry, J.J.; McManus, G.J.; Zaworotko, M.J. "4-Methoxypyridine-(pyridine-2,6-dicarboxylato-N,O,O') copper (II)", J. Chem. Cryst., 2004, 34(12), 877-881.
• Perry, J.J.; McManus, G.J.; Zaworotko, M. J. "Sextuplet phenyl embrace in a metal-organic Kagome lattice", Chem. Commun., 2004, (22), 2534-2535. (Top 5 most viewed articles: February 02/05 – May 09/05)
• McManus, G. J.; Wang, Z.; Zaworotko, M.J. "Suprasupermolecular Chemistry: Infinite Networks from Nanoscale Building Blocks", Cryst. Growth Des., 2004, 4(1), 11-13. (Cover article).
• Wagner, B.D.; Fitzpatrick, S.J.; McManus, G.J. "Fluorescence Suppression of 7-Methoxycoumarin upon Inclusion into Cyclodextrins", J. Incl. Phen., 2003, 47(3-4), 187-192.
• Abourahma, H.; Moulton, B.; McManus G.J.; Walsh, R.D.B.; Zaworotko, M.J. "Functional Coordination Polymers", Macromol. Symp., 2003, 196, 213-227.
• Moulton, B.; Abourahma, H.; Bradner, M. W.; Lu, J.; McManus, G. J.; Zaworotko, M. J. "A new 65.8 topology and a distorted 65.8 CdSO4 topology: two new supramolecular isomers of [M2(bdc)2(L)2]n coordination polymers", Chem. Commun., 2003, (12), 1342-1343.
• Wagner, B.D.; McManus, G.J. "Enhancement of the fluorescence and stability of o-phthalaldehyde derived isoindoles of amino acids using hydroxypropyl-β-cyclodextrin", Anal. Biochem., 2003, 317(2), 233-239.
• Wagner, B.D.; McManus, G.J.; Moulton, B.; Zaworotko, M.J. "Exciplex fluorescence of {[Zn(bipy)1.5(NO3)2] • CH3OH • 1/2 pyrene}n: a coordination polymer containing intercalated pyrene molecules (bipy = 4,4'-bipyridine)", Chem. Commun., 2002, (18), 2176-2177.

• Southwest Florida Community Foundation: Community Impact Grant: Combating Climate Change in SWFL via a summer research program for high school students. PI. 2020.
• The Consortium for Medical Marijuana Clinical Outcomes Research: Rapid identification and quantification of heavy metals and microplastics in CBD oil. PI. 2019.
• National Science Foundation – Major Research Instrumentation (MRI): Acquisition of a Single Crystal X-Ray Diffractometer to Enhance Undergraduate Research and Education in South Florida; Award Number: 1919785; PI. 2019.
• Argonne National Lab, Advanced Photon Source, General User Proposal: Elucidating the structure of large Metal-Organic Polyhedra; GUP: 64495; PI. 2019.
• FGCU Communities in Transition Initiative Award, coPI. 2018 & 2019.
• FGCU Holmes Development Fund Award. PI. 2018.
• FGCU Seidler Student/Faculty Scholarly Collaboration Fellowship. PI. 2016 & 2018.
• National Science Foundation – Major Research Instrumentation (MRI): Acquisition of a 400 MHz NMR Spectrometer to Support Undergraduate Research and Chemical Education at Florida Gulf Coast University; Award Number: 1530959; SP. 2016.